SCHEMBL1702986

SCHEMBL1702986

Clc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(Cl)c4)cc3)cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HDAC6 Q9UBN7 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
TP53 P04637 2/20 0.40
PGR P06401 1/20 0.39
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL512533 1.00 MAPT (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL258156 1.00 MAPT (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL12533861 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL9581080 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL20872019 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL16858263 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL19801911 0.96 CYP1A2 (0.45) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL15713960 0.94 TAAR1 (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL8100812 0.94 MAPT (0.48) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL9321690 0.92 MAPT (0.50) MAPTALDH1A1CYP1A2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-4047949-A Composite layered imaging member for electrophotography XEROX CORPORATION (US) 1977-09-13 US claimed
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7867677-B2 Imaging member having first and second charge transport layers XEROX CORPORATION (US) 2011-01-11 US disclosed
US-7867677-B2 Imaging member having first and second charge transport layers XEROX CORPORATION (US) 2011-01-11 US disclosed
US-7811728-B2 Imaging members and process for preparing same XEROX CORPORATION (US) 2010-10-12 US disclosed
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 US disclosed
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4431722-A POLYCYCLIC QUINONE PIGMENT DISPERSED IN A RESIN BINDER AS CHARGE GENERATING LAYER; ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-02-14 US disclosed
US-4346158-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1982-08-24 US disclosed
US-4265990-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1981-05-05 US disclosed
US-4123269-A Electrostatographic photosensitive device comprising hole injecting and hole transport layers XEROX CORPORATION (US) 1978-10-31 US disclosed