SCHEMBL258156

SCHEMBL258156

Clc1cccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc(N(c5ccccc5)c5cccc(Cl)c5)cc4)cc3)cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HDAC6 Q9UBN7 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
TP53 P04637 2/20 0.40
PGR P06401 1/20 0.39
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702986 1.00 MAPT (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL512533 1.00 MAPT (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL12533861 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL9581080 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL20872019 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL16858263 0.98 CYP1A2 (0.46) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL19801911 0.96 CYP1A2 (0.45) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL15713960 0.94 TAAR1 (0.44) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL8100812 0.94 MAPT (0.48) MAPTALDH1A1CYP1A2TDP1L3MBTL1
SCHEMBL9321690 0.92 MAPT (0.50) MAPTALDH1A1CYP1A2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 737 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2270601-B1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER WITH A FLUORINATED POLYMER AND A CORE SHELL COMPONENT XEROX CORP (US) 2017-11-29 EP claimed
EP-2270600-B1 Core shell photoconductors XEROX CORP (US) 2017-04-19 EP claimed
US-9411251-B2 Photoconductor containing a charge transport layer having an arylamine hole transport material XEROX CORPORATION (US) 2016-08-09 US claimed
EP-2290452-B1 POSS melamine overcoated photoconductors XEROX CORP (US) 2016-06-01 EP claimed
US-20150037715-A1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER HAVING AN ARYLAMINE HOLE TRANSPORT MATERIAL XEROX CORPORATION (US) 2015-02-05 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8481237-B2 Photoconductor overcoat layer XEROX CORPORATION (US) 2013-07-09 US claimed
US-8465888-B2 Photoconductor undercoat layer XEROX CORPORATION (US) 2013-06-18 US claimed
US-8310509-B2 Direct digital marking systems XEROX CORPORATION (US) 2012-11-13 US claimed
US-8305405-B2 Electrostatic digital offset/flexo printing XEROX CORPORATION (US) 2012-11-06 US claimed
US-20070292789-A1 Polyphenyl ether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292787-A1 Flexible imaging member such as a belt including a photogenerating layer and a charge transport mixture of an antioxidant and a polyphenyl thioether that may contain phenoxy groups, e.g., 1-phenoxy-3-[[3-(phenylthio)phenyl]thio]benzene; increased surface hardness, wear resistance and solvent resistance XEROX CORPORATION 2007-12-20 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292782-A1 Polyphenyl ether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292793-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292790-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292786-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292784-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292783-A1 Ether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed