Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845708 | 0.82 | GRIA4 (0.35) | GRIA4 | |
| SCHEMBL17030639 | 0.80 | PER2 (0.44) | GRIA4 | |
| SCHEMBL28305215 | 0.78 | CA1 (0.32) | GRIA4 | |
| SCHEMBL12745326 | 0.75 | — | — | |
| SCHEMBL10510598 | 0.75 | TSHR (0.36) | GRIA4 | |
| SCHEMBL598563 | 0.73 | GRIA4 (0.32) | GRIA4 | |
| SCHEMBL11715156 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL777392 | 0.69 | CA12 (0.39) | GRIA4 | |
| SCHEMBL17149388 | 0.67 | GRIA4 (0.37) | GRIA4 | |
| SCHEMBL18215409 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2674428-B1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2007756-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2015-08-26 | — | — | EP | disclosed |