Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 5/20 | 0.44 |
| ▸ | CRY1 | Q16526 | 4/20 | 0.44 |
| ▸ | CRY2 | Q49AN0 | 4/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030573 | 0.80 | GRIA4 (0.30) | GRIA4 | |
| SCHEMBL9953090 | 0.79 | PER2 (0.45) | PER2CRY1CRY2GRIA4CA2 | |
| SCHEMBL12379993 | 0.79 | PER2 (0.45) | PER2CRY1CRY2GRIA4CA2 | |
| SCHEMBL13547818 | 0.74 | PER2 (0.41) | PER2CRY1CRY2GRIA4 | |
| SCHEMBL2843643 | 0.73 | — | — | |
| SCHEMBL7549455 | 0.70 | GPR84 (0.47) | — | |
| SCHEMBL27887729 | 0.69 | — | — | |
| SCHEMBL91255 | 0.67 | — | — | |
| SCHEMBL18215409 | 0.67 | — | — | |
| SCHEMBL21241594 | 0.67 | PER2 (0.36) | PER2CRY1CRY2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007756-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2015-08-26 | — | — | EP | disclosed |