SCHEMBL17030716

SCHEMBL17030716

c1ccc(-n2c(-c3ccccc3C3c4ccccc4-c4ccccc43)nnc2-c2ccccc2-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 5/20 0.36
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
TSHR P16473 2/20 0.34
HPGD P15428 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
AKT1 P31749 1/20 0.33
IL1R1 P14778 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
NTRK1 P04629 1/20 0.33
ALOX5 P09917 1/20 0.33
IDO1 P14902 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPK8 P45983 1/20 0.33
TDO2 P48775 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17030719 0.89 KDM4E (0.55) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL10111060 0.83 KDM4E (0.49) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL17614702 0.79 AVPR1A (0.50) KDM4EALDH1A1KMT2AMEN1TSHR
SCHEMBL19732861 0.77 KDM4E (0.41) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL10111055 0.76 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1TSHR
SCHEMBL18932081 0.72 RECQL (0.58) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL28453269 0.72 L3MBTL1 (0.67) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL10111054 0.71 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL16446610 0.71 ALDH1A1 (0.37) KDM4EL3MBTL1ATMALDH1A1KMT2A
SCHEMBL13133990 0.70 KDM4E (0.43) KDM4EL3MBTL1ATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150243902-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-08-27 US disclosed
US-20150243902-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-08-27 US disclosed