Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10111060 | 0.94 | KDM4E (0.49) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL17030716 | 0.89 | KDM4E (0.44) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10111055 | 0.85 | KDM4E (0.46) | KDM4EATML3MBTL1ALDH1A1TSHR | |
| SCHEMBL19732861 | 0.84 | KDM4E (0.41) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18932081 | 0.81 | RECQL (0.58) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28453269 | 0.81 | L3MBTL1 (0.67) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10111054 | 0.80 | KDM4E (0.47) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13133990 | 0.79 | KDM4E (0.43) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18119531 | 0.79 | KDM4E (0.53) | KDM4EATML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL17030715 | 0.78 | KDM4E (0.49) | KDM4EATML3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-12-21 | — | — | US | disclosed |
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-12-21 | — | — | US | disclosed |
| US-20160087227-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-03-24 | — | — | US | disclosed |
| US-20160087227-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-03-24 | — | — | US | disclosed |
| US-20150243902-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-08-27 | — | — | US | disclosed |
| US-20150243902-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | CYP2C9, CYP2C19, INTS9 | KDM4E 2376/4885ATM 2967/4885L3MBTL1 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.