Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123712 | 0.80 | HDAC1 (0.52) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL8192122 | 0.80 | HDAC1 (0.52) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL11625027 | 0.78 | HDAC1 (0.50) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL1436032 | 0.78 | HDAC1 (0.50) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL8324617 | 0.78 | UBE2T (0.54) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL351856 | 0.78 | NNMT (0.61) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL5916417 | 0.77 | UBE2T (0.53) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8327897 | 0.77 | UBE2T (0.53) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL25307873 | 0.75 | UBE2T (0.51) | HDAC1HDAC6ADRA2AADRA2BADRA2C | |
| SCHEMBL21004360 | 0.75 | HDAC1 (0.61) | HDAC1HDAC6ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | HDAC1 290/4885HDAC6 76/4885ADRA2A 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.