SCHEMBL17033599

SCHEMBL17033599

c1cc(-c2ccncc2)cc(-n2c3ccccc3c3ccc4cc5c6ccccc6c6ccccc6n5c4c32)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
DHFR P00374 1/20 0.35
HTR6 P50406 1/20 0.34
GRM5 P41594 1/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
IMPDH2 P12268 1/20 0.33
MAPK10 P53779 4/20 0.33
MAPK9 P45984 3/20 0.33
PDE10A Q9Y233 1/20 0.33
MAPK8 P45983 1/20 0.33
PRKCI P41743 1/20 0.33
CHEK1 O14757 3/20 0.32
HSP90AA1 P07900 1/20 0.32
MKNK1 Q9BUB5 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033622 0.92 ATM (0.39) HSD17B1HSD17B2DHFRMAPTMEN1
SCHEMBL16067125 0.91 HSD17B1 (0.34) HSD17B1HSD17B2DHFRHTR6GRM5
SCHEMBL17033654 0.89 MAPT (0.41) HSD17B1HSD17B2DHFRGRM5MAPT
SCHEMBL17033605 0.88 PDE10A (0.34) HSD17B1HSD17B2MAPTMEN1KMT2A
SCHEMBL17033571 0.87 DHFR (0.34) HSD17B1HSD17B2DHFRHTR6GRM5
SCHEMBL17033452 0.86 GRM5 (0.35) HSD17B1HSD17B2DHFRGRM5MAPT
SCHEMBL17033637 0.86 HSD17B1 (0.38) HSD17B1HSD17B2MEN1KMT2AGAA
SCHEMBL17033660 0.85 KDM4E (0.34) MEN1KMT2AGAAPDE10AKDM4E
SCHEMBL17033601 0.85 KDM4E (0.36) MAPTMEN1KMT2AGAAPDE10A
SCHEMBL17033597 0.84 HTR1A (0.43) DHFRGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed