Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77792 | 0.91 | SMPD1 (0.47) | SMPD1OPRM1SPHK1LMNACA2 | |
| SCHEMBL510082 | 0.89 | SMPD1 (0.44) | SMPD1OPRM1LMNACA2DNM1 | |
| SCHEMBL28733012 | 0.79 | ACE2 (0.44) | ACE2SMPD1PRKD3PRKCGPRKCB | |
| SCHEMBL1116716 | 0.77 | FAAH (0.39) | SMPD1OPRM1SPHK1LMNAADH1B | |
| SCHEMBL22444285 | 0.76 | SMPD1 (0.46) | SMPD1LMNACA2 | |
| SCHEMBL8416793 | 0.76 | SMPD1 (0.46) | SMPD1LMNACA2 | |
| SCHEMBL31187915 | 0.76 | ACE2 (0.67) | ACE2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL995479 | 0.76 | ACE2 (0.67) | ACE2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL28224288 | 0.76 | ACE2 (0.60) | ACE2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL4811228 | 0.75 | OPRM1 (0.39) | SMPD1OPRM1SPHK1LMNAADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440162-A1 | CROSSLINKED BIOABSORBABLE MEDICAL DEVICES | Boston Scientific Scimed, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144325-A1 | CROSSLINKED BIOABSORBABLE MEDICAL DEVICES | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-12-16 | — | — | WO | disclosed |