SCHEMBL1703382

SCHEMBL1703382

NC(=O)c1c(F)c(F)c(F)c(C(N)=O)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
POLB P06746 1/20 0.38
HTT P42858 2/20 0.37
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
PARP1 P09874 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161645 0.97 CES2 (0.42) CES2CES1POLBHTTLMNA
SCHEMBL12544632 0.94 CES2 (0.40) CES2CES1POLBHTTLMNA
Bromide SCHEMBL29086958 0.94 CES2 (0.40) CES2CES1POLBHTTLMNA
SCHEMBL811680 0.94 POLB (0.41) CES2CES1POLBHTTLMNA
SCHEMBL9147301 0.90 CES2 (0.42) CES2CES1POLBHTTLMNA
SCHEMBL28298959 0.90 POLB (0.39) CES2CES1POLBHTTLMNA
SCHEMBL8895324 0.84 POLB (0.32) CES2CES1POLB
SCHEMBL707937 0.82 ESR1 (0.39) CES2CES1POLBHTT
SCHEMBL3145740 0.82 POLB (0.35) CES2CES1POLBHTT
SCHEMBL3293891 0.80 CES2 (0.41) CES2CES1POLBLMNAF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5230002-A None JP disclosed
EP-2442397-B1 ELECTROLYTIC SOLUTION AND LITHIUM-ION SECONDARY BATTERY UTILIZING THE SAME ASAHI CHEMICAL IND (JP) 2016-10-05 EP disclosed
US-9118088-B2 Electrolyte solution and lithium ion secondary battery using the same ASAHI KASEI E-MATERIALS CORPORATION (JP) 2015-08-25 US disclosed
US-20120141878-A1 ELECTROLYTE SOLUTION AND LITHIUM ION SECONDARY BATTERY USING THE SAME ASAHI KASEI E-MATERIALS CORPORATION (JP) 2012-06-07 US disclosed
EP-2442397-A1 ELECTROLYTIC SOLUTION AND LITHIUM ION SECONDARY BATTERY UTILIZING SAME Asahi Kasei E-Materials Corporation (JP) 2012-04-18 EP disclosed
US-7741426-B2 Reacting a fluorinated phthalamide, isophthalamide or terephthalamide with NaOCl or NaOBr and NaOH; polymerizing the product with a tetracarboxylic acid or derivative to form a polyamic acid, which is cyclized to form a polyimide; low dielectric constant and refractive index; excellent water repellency NIPPON SHOKUBAI CO., LTD (JP) 2010-06-22 US disclosed
US-20060142539-A1 Method for production of fluorinated phenylenediamine NIPPON SHOKUBAI CO., LTD. (JP) 2006-06-29 US disclosed
EP-1636166-A2 METHOD FOR PRODUCTION OF FLUORINATED PHENYLENEDIAMINE Nippon Shokubai Co., Ltd. (JP) 2006-03-22 EP disclosed
WO-2004113267-A2 METHOD FOR PRODUCTION OF FLUORINATED PHENYLENEDIAMINE NIPPON SHOKUBAI CO., LTD. (JP) 2004-12-29 WO disclosed
US-6362365-B1 DEFLUORINATION OF THE TETRAFUOROISOPHALATE DERIVATIVE USING ORGANO ALKYL METALLIC COMPOUND TO ALKYLATE AT THE 6 POSITION AND THEN DECARBOXYLATION CLARIANT GMBH (DE) 2002-03-26 US disclosed
JP-H05230002-A TETRAFLUOROISOPHTHALAMIDE, ITS PRODUCTION AND PRODUCTION OF TETRAFLUOROISOPHTHALIC ACID NIPPON LIGHT METAL CO LTD 1993-09-07 JP disclosed