SCHEMBL17033901

SCHEMBL17033901

c1cncc(-c2ccc(-c3nc(-n4c5ccccc5c5ccc6c(cc7c8ccccc8c8ccccc8n76)c54)nc4ccccc34)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.39
HPGD P15428 4/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.37
LMNA P02545 1/20 0.36
RAD51 Q06609 1/20 0.35
LCK P06239 1/20 0.34
CYP11B1 P15538 1/20 0.34
USP1 O94782 4/20 0.33
WDR48 Q8TAF3 4/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP11B2 P19099 1/20 0.33
PDE5A O76074 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033899 0.92 ALDH1A1 (0.44) DHODHHPGDALDH1A1KDM4EMAPT
SCHEMBL17033921 0.90 ALDH1A1 (0.46) HPGDALDH1A1KDM4EMAPTNPSR1
SCHEMBL17033923 0.87 HPGD (0.41) DHODHHPGDALDH1A1MAPTNPSR1
SCHEMBL17033922 0.86 ALDH1A1 (0.36) DHODHHPGDALDH1A1KDM4EMAPT
SCHEMBL16066270 0.83 DHODH (0.39) DHODHHPGDALDH1A1KDM4EMAPT
SCHEMBL17033887 0.82 ALDH1A1 (0.37) HPGDALDH1A1KDM4EMAPTNPSR1
SCHEMBL17033748 0.80 DHODH (0.41) DHODHMAPTCYP11B1CYP11B2PDE5A
SCHEMBL21213093 0.80 DHODH (0.42) DHODHHPGDALDH1A1KDM4EMAPT
SCHEMBL17408646 0.79 ALOX12 (0.39) DHODHHPGDALDH1A1KDM4EMAPT
SCHEMBL16066272 0.79 ALDH1A1 (0.38) DHODHHPGDALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed