SCHEMBL17408646

SCHEMBL17408646

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccnc6)c6ccccc6c54)nc4ccccc34)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 1/20 0.39
MDM2 Q00987 1/20 0.38
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
METAP2 P50579 1/20 0.35
RAB9A P51151 1/20 0.35
GSR P00390 1/20 0.33
DHODH Q02127 1/20 0.33
MAPK1 P28482 2/20 0.33
GAA P10253 1/20 0.33
CYP11B1 P15538 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17408325 0.96 ALOX12 (0.39) ALOX12MDM2MAPTALDH1A1HPGD
SCHEMBL19979388 0.94 MDM2 (0.41) ALOX12MDM2MAPTALDH1A1HPGD
SCHEMBL17408379 0.94 MAPT (0.39) ALOX12MDM2MAPTALDH1A1HPGD
SCHEMBL17408416 0.92 ALOX12 (0.42) ALOX12MDM2MAPTALDH1A1HPGD
SCHEMBL15860187 0.91 KDM4E (0.41) MAPTALDH1A1HPGDKDM4ENPSR1
SCHEMBL17408633 0.91 MDM2 (0.40) ALOX12MDM2MAPTALDH1A1HPGD
SCHEMBL16706426 0.90 KDM4E (0.42) MAPTALDH1A1HPGDKDM4ENPSR1
SCHEMBL17408376 0.89 ALDH1A1 (0.41) MAPTALDH1A1HPGDKDM4ENPSR1
SCHEMBL17408648 0.88 KDM4E (0.41) MAPTALDH1A1HPGDKDM4ENPSR1
SCHEMBL22479817 0.88 ALOX12 (0.45) ALOX12MDM2MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10763443-B2 Compound for organic electronic element, organic electronic element using the same, and electronic device thereof DUK SAN NEOLUX CO., LTD (KR) 2020-09-01 US disclosed
US-10672992-B2 Compound for organic electronic element, organic electronic element using the same, and electronic device thereof DUK SAN NEOLUX CO., LTD (KR) 2020-06-02 US disclosed
US-20190173023-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2019-06-06 US disclosed
US-20180083204-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083204-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-03-22 US disclosed
US-20160005981-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-07 US disclosed
US-20160005981-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190173023-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ESR1 ALOX12 39/4885MDM2 1013/4885MAPT 792/4885
US-10763443-B2 Compound for organic electronic element, organic electronic element using the same, and electronic device thereof NFE2L2, OR51E2, ESR1 ALOX12 39/4885MDM2 1013/4885MAPT 792/4885
US-20180083204-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ESR1 ALOX12 39/4885MDM2 1013/4885MAPT 792/4885
US-10672992-B2 Compound for organic electronic element, organic electronic element using the same, and electronic device thereof NFE2L2, OR51E2, ESR1 ALOX12 39/4885MDM2 1013/4885MAPT 792/4885
US-20160005981-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE THEREOF NFE2L2, OR51E2, ESR1 ALOX12 39/4885MDM2 1013/4885MAPT 792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.