Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940469 | 0.86 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL18940473 | 0.85 | THRB (0.51) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL15502156 | 0.83 | THRB (0.42) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL13476245 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2MAPTALDH1A1HPGDHTT | |
| SCHEMBL5694355 | 0.81 | TDP1 (0.56) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL21611657 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HPGDHTTTDP1 | |
| SCHEMBL13476244 | 0.80 | TDP1 (0.48) | SMN1; SMN2LMNAMAPTNPC1RAB9A | |
| SCHEMBL3656039 | 0.79 | TSHR (0.54) | SMN1; SMN2LMNAPPARGPPARDPPARA | |
| SCHEMBL200763 | 0.79 | TDP1 (0.46) | SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL19808790 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1HPGDHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951162-B2 | UV-crosslinkable polymer composition | TESA SE (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20170166671-A1 | UV-CROSSLINKABLE POLYMER COMPOSITION | TESA SE (DE) | 2017-06-15 | — | — | US | disclosed |
| WO-2015124593-A1 | UV-CROSSLINKABLE POLYMER COMPOSITION | TESA SE (DE) | 2015-08-27 | — | — | WO | disclosed |