Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030191 | 0.89 | TDP1 (0.55) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1108095 | 0.87 | TDP1 (0.48) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL649097 | 0.83 | TDP1 (0.51) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31426927 | 0.83 | TDP1 (0.51) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9780126 | 0.83 | TDP1 (0.68) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1592876 | 0.82 | TDP1 (0.60) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17034019 | 0.81 | SMN1; SMN2 (0.41) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17459123 | 0.81 | L3MBTL1 (0.64) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9469278 | 0.81 | TDP1 (0.49) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5706209 | 0.81 | CYP1A2 (0.56) | TDP1L3MBTL1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765764-B2 | 2-acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130079351-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA, INC. (JP) | 2013-03-28 | — | — | US | disclosed |
| EP-1153085-B1 | DISAZO DYES AND INKS CONTAINING THEM | FUJIFILM IMAGING COLORANTS LTD (GB) | 2006-05-17 | — | — | EP | disclosed |
| US-6712893-B1 | BLACK INKS WITH GOOD STORAGE STABILITY; IMAGES WITH GOOD OPTICAL DENSITY AND COLORFASTNESS | AVECIA LIMITED (GB) | 2004-03-30 | — | — | US | disclosed |
| EP-1153085-A2 | DISAZO DYES AND INKS CONTAINING THEM | Avecia Limited (GB) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000043453-A2 | DISAZO DYES AND INKS CONTAINING THEM | AVECIA LIMITED (GB) | 2000-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079351-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | MPL, JAK2, ABL1 | TDP1 4760/4885L3MBTL1 1136/4885MAPT 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.