SCHEMBL17035137

SCHEMBL17035137

Brc1c2ccccc2c(-c2ccc3c(c2)nc(-c2ccccc2)c2ccc4ccccc4c23)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.38
ESR2 Q92731 4/20 0.38
PRNP P04156 1/20 0.36
MAPT P10636 4/20 0.35
LMNA P02545 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
RECQL P46063 1/20 0.35
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
ADORA2A P29274 1/20 0.34
NUDT1 P36639 1/20 0.34
DHFR P00374 1/20 0.34
HTT P42858 2/20 0.34
POLB P06746 1/20 0.34
HSP90AA1 P07900 1/20 0.34
GAA P10253 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17035032 0.86 ESR1 (0.38) ESR1ESR2MAPTLMNANPC1
SCHEMBL17035069 0.86 MEN1 (0.44) ESR1ESR2MAPTLMNANPC1
SCHEMBL17997983 0.86 LMNA (0.36) ESR1ESR2PRNPMAPTLMNA
SCHEMBL18200643 0.85 LMNA (0.45) ESR1ESR2MAPTLMNAKDM4E
SCHEMBL17035044 0.84 ESR1 (0.39) ESR1ESR2MAPTLMNANPC1
SCHEMBL17035033 0.84 CYP11B1 (0.43) ESR1ESR2MAPTNPC1RAB9A
SCHEMBL17035136 0.83 PRNP (0.39) PRNPMAPTLMNANPC1RAB9A
SCHEMBL18200486 0.83 ESR1 (0.44) ESR1ESR2LMNAADORA2ANUDT1
SCHEMBL20240269 0.82 PRNP (0.49) PRNPMAPTADORA2ANUDT1HTT
SCHEMBL17035064 0.82 ESR1 (0.37) ESR1ESR2LMNAKDM4EDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9871208-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-16 US disclosed
US-20150243908-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-27 US disclosed
US-20150243908-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150243908-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ESR1 175/4885ESR2 721/4885PRNP 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.