Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.33 |
| ▸ | CFB | P00751 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897916 | 0.88 | PIN1 (0.38) | PIN1L3MBTL1GSK3BMMP13ALK | |
| SCHEMBL897789 | 0.78 | L3MBTL1 (0.36) | PIN1L3MBTL1GSK3BALKCFB | |
| SCHEMBL897791 | 0.71 | CYP3A4 (0.38) | CNR1 | |
| SCHEMBL28319539 | 0.68 | L3MBTL1 (0.38) | PIN1L3MBTL1GSK3BALKCCR9 | |
| SCHEMBL23639678 | 0.67 | L3MBTL1 (0.41) | PIN1L3MBTL1GSK3BALKCCR9 | |
| SCHEMBL17434650 | 0.66 | ALK (0.38) | L3MBTL1ALKCFB | |
| SCHEMBL28588337 | 0.65 | PIN1 (0.45) | PIN1L3MBTL1ALK | |
| SCHEMBL897523 | 0.64 | MAPT (0.36) | L3MBTL1CNR1 | |
| SCHEMBL20004875 | 0.64 | GSK3B (0.35) | PIN1GSK3BALKCFB | |
| SCHEMBL6218634 | 0.63 | PIN1 (0.48) | PIN1L3MBTL1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |