SCHEMBL4273722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19066469	1.00	ADRA1D (0.39)	ADRA1DADRA1AKMT2APDE4BCASP3
	SCHEMBL4278443	0.88	KDM4E (0.47)	KMT2APDE4BTSHRALDH1A1KDM4E
	SCHEMBL15521514	0.87	ADRA1D (0.42)	ADRA1DADRA1AKMT2ATSHRALDH1A1
	SCHEMBL24297148	0.86	ADRA1D (0.44)	ADRA1DADRA1AKMT2ATSHRALDH1A1
	SCHEMBL17037218	0.86	ADRA1A (0.50)	ADRA1DADRA1AKMT2ATSHRALDH1A1
	SCHEMBL31239065	0.86	ADRA1A (0.50)	ADRA1DADRA1AKMT2ATSHRALDH1A1
	SCHEMBL31239024	0.84	ADRA1D (0.41)	ADRA1DADRA1AKMT2ACASP3TSHR
	SCHEMBL19066428	0.84	ADRA1D (0.41)	ADRA1DADRA1AKMT2ACASP3TSHR
	SCHEMBL17037230	0.83	TSHR (0.41)	KMT2APDE4BTSHRALDH1A1KDM4E
	SCHEMBL4280199	0.83	TSHR (0.41)	KMT2APDE4BTSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.