SCHEMBL17038457

SCHEMBL17038457

c1ccc(-c2ccc(-c3cccc4c3sc3c(-n5c6ccccc6c6ccc(-n7c8ccccc8c8ccccc87)cc65)cccc34)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LIMK1 P53667 1/20 0.36
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPK14 Q16539 1/20 0.34
HDAC4 P56524 1/20 0.33
PDE6D O43924 1/20 0.33
PRKDC P78527 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
F9 P00740 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17038455 0.97 KDM4E (0.39) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL24677422 0.93 L3MBTL1 (0.41) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL17038425 0.92 L3MBTL1 (0.45) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL17038426 0.91 L3MBTL1 (0.41) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL23072418 0.91 ATM (0.39) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL24677556 0.89 KDM4E (0.40) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL17038418 0.89 L3MBTL1 (0.44) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL17038454 0.88 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1
SCHEMBL17057179 0.88 ALOX5 (0.36) KDM4EATML3MBTL1LIMK1ALOX5
SCHEMBL17038424 0.88 ATM (0.41) KDM4EATML3MBTL1LIMK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707423-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 US disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed
US-20150243894-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10707423-B2 Organic electroluminescent materials and devices OCIAD1, OXA1L, SLCO2B1 KDM4E 3237/4885ATM 3925/4885L3MBTL1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.