SCHEMBL24677422

SCHEMBL24677422

c1ccc(-c2ccc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc4c3sc3c(-c5ccccc5)cccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
LIMK1 P53667 1/20 0.36
HDAC4 P56524 1/20 0.36
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 2/20 0.34
PDE6D O43924 1/20 0.33
MAPK14 Q16539 1/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
KMT2A Q03164 2/20 0.31
IL1R1 P14778 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
HSD17B10 Q99714 1/20 0.30
RAC2 P15153 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24677423 0.95 L3MBTL1 (0.46) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL24677556 0.94 KDM4E (0.40) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL23072418 0.93 ATM (0.39) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL17038457 0.93 KDM4E (0.37) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL10331654 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL17640315 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL17038455 0.90 KDM4E (0.39) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL15989419 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL25496651 0.90 ALOX5 (0.36) L3MBTL1KDM4EATMLIMK1HDAC4
SCHEMBL17228758 0.89 L3MBTL1 (0.43) L3MBTL1KDM4EATMLIMK1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM L3MBTL1 1135/4885KDM4E 3594/4885ATM 1277/4885
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 L3MBTL1 888/4885KDM4E 2090/4885ATM 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.