Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158933 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL29382443 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL17037958 | 0.85 | HPGD (0.67) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| Propane SCHEMBL626692 | 0.84 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL19833679 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL1554210 | 0.81 | THRA (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1THRA | |
| SCHEMBL30323029 | 0.81 | THRA (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1THRA | |
| SCHEMBL592846 | 0.81 | THRA (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1THRA | |
| SCHEMBL21953325 | 0.81 | HPGD (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL17035290 | 0.81 | HPGD (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239928-A1 | CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239928-A1 | CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS | CCL11, SERPINA6, CXCL10 | ALDH1A1 4581/4885SMN1; SMN2 3512/4885RAB9A 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.