Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19833679 | 0.98 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL29382443 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL158933 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| Acrylamide SCHEMBL28131676 | 0.87 | ALDH1A1 (0.40) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL17038474 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL21573033 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL24277990 | 0.83 | HPGD (0.44) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL26735842 | 0.83 | HPGD (0.44) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL702196 | 0.83 | PTPN1 (0.62) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD | |
| SCHEMBL29403777 | 0.83 | PTPN1 (0.62) | SMN1; SMN2RAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041479-A1 | Tissue Sealant Compositions, Vascular Closure Devices, and Uses Thereof | MEDIBEACON, INC. | 2012-02-16 | — | — | US | disclosed |
| US-7776528-B2 | Radiative decay engineering | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-08-17 | — | — | US | disclosed |
| US-20050202464-A1 | Radiative decay engineering | UNIVERSITY OF MARYLAND, BALTIMORE | 2005-09-15 | — | — | US | disclosed |