Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423421 | 0.81 | PTGS2 (0.66) | PTGS2 | |
| SCHEMBL8640349 | 0.79 | PTGS2 (0.43) | PTGS2L3MBTL1LTA4HLMNA | |
| SCHEMBL7931174 | 0.78 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL8672850 | 0.78 | PTGS2 (0.59) | PTGS2L3MBTL1LMNAMAPT | |
| Water SCHEMBL11131807 | 0.77 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL21101966 | 0.76 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL20714921 | 0.75 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL7931176 | 0.75 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL5316867 | 0.75 | PTGS2 (0.66) | PTGS2 | |
| SCHEMBL10977179 | 0.75 | L3MBTL1 (0.43) | L3MBTL1LTA4HLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481645-B2 | Composition, synthesis, and use of a new class of isonitriles | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2016-11-01 | — | — | US | disclosed |
| US-9481645-B2 | Composition, synthesis, and use of a new class of isonitriles | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2016-11-01 | — | — | US | disclosed |
| US-20150239835-A1 | COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150239835-A1 | COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239835-A1 | COMPOSITION, SYNTHESIS, AND USE OF A NEW CLASS OF ISONITRILES | CYP3A4, UGT1A4, INTS9 | PTGS2 3479/4885POLB 1321/4885ATM 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.