Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928371 | 1.00 | TRPM8 (0.40) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL6911471 | 0.74 | TRPM8 (0.48) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL11855364 | 0.73 | TRPM8 (0.47) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL1674809 | 0.73 | TRPM8 (0.52) | TRPM8TRPA1EPHX1KCNA5CA1 | |
| SCHEMBL2123054 | 0.73 | EPHX1 (0.49) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL18626368 | 0.70 | TRPM8 (0.52) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL33532890 | 0.68 | EPHX1 (0.41) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL19067387 | 0.67 | TRPM8 (0.48) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL9514707 | 0.67 | TRPM8 (0.41) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL19928370 | 0.66 | EPHX1 (0.57) | TRPM8TRPA1EPHX1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | SRMS, AADAC, CYP3A4 | TRPM8 4850/4885TRPA1 3794/4885EPHX1 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.