Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17038560 | 0.87 | SLC6A4 (0.50) | SLC6A4ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19200474 | 0.81 | SLC6A4 (0.49) | SLC6A4ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7329609 | 0.80 | SLC6A4 (0.46) | SLC6A4ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL20901254 | 0.78 | SLC6A4 (0.39) | SLC6A4ALDH1A1LDHAACACBMMP1 | |
| SCHEMBL10495976 | 0.73 | MMP1 (0.41) | MMP1 | |
| SCHEMBL9502392 | 0.73 | MMP1 (0.41) | MMP1 | |
| SCHEMBL16462269 | 0.73 | ALDH1A1 (0.54) | SLC6A4ALDH1A1CYP2C19LDHAMMP1 | |
| SCHEMBL16228054 | 0.73 | CA2 (0.58) | SLC6A4ALDH1A1LDHAMMP1 | |
| SCHEMBL16228052 | 0.73 | CA2 (0.58) | SLC6A4ALDH1A1LDHAMMP1 | |
| SCHEMBL7276267 | 0.72 | MMP1 (0.41) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452215-B2 | Bourvadin derivatives and therapeutic uses thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150238562-A1 | BOURVADIN DERIVATIVES AND THERAPEUTIC USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238562-A1 | BOURVADIN DERIVATIVES AND THERAPEUTIC USES THEREOF | RPL27, EIF4E, RPL30 | SLC6A4 4467/4885ALDH1A1 3270/4885CYP1A2 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.