Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344789 | 0.89 | NR1I2 (0.37) | NR1I2KDM4EHPGDALDH1A1HTT | |
| SCHEMBL20033899 | 0.89 | NR1I2 (0.40) | NR1I2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL17029033 | 0.87 | NR1I2 (0.39) | NR1I2KDM4EHPGDALDH1A1HTT | |
| SCHEMBL17039244 | 0.87 | NR1I2 (0.42) | NR1I2KDM4EHPGDALDH1A1HTT | |
| SCHEMBL20344788 | 0.87 | NR1I2 (0.42) | NR1I2KDM4EHPGDALDH1A1HTT | |
| SCHEMBL20344833 | 0.85 | NR1I2 (0.41) | NR1I2KMT2APDE4BPDCD1CD274 | |
| SCHEMBL17029005 | 0.85 | NR1I2 (0.42) | NR1I2KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL17029006 | 0.84 | NR1I2 (0.41) | NR1I2KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL17039260 | 0.84 | NR1I2 (0.50) | NR1I2KCNH2AVPR1B | |
| SCHEMBL17029021 | 0.82 | NR1I2 (0.45) | NR1I2PDCD1CD274AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107913-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2018-07-04 | — | — | EP | disclosed |
| WO-2015126765-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |