Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12055674 | 0.86 | CRHBP (0.50) | APPMAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17037126 | 0.82 | CRHBP (0.47) | MAPTHTTALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL10031374 | 0.82 | HTT (0.51) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL17037090 | 0.80 | SMN1; SMN2 (0.49) | MAPTHTTALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL17037091 | 0.78 | MAPT (0.49) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13649835 | 0.78 | ALDH1A1 (0.50) | MAPTHTTALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL18252673 | 0.77 | HTT (0.50) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL749155 | 0.75 | CRHBP (0.53) | APPMAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL17040019 | 0.74 | ALDH1A1 (0.57) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29164288 | 0.74 | SNCA (0.56) | SNCACTSVCTSLAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260451-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150239901-A1 | Method For Producing Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239901-A1 | Method For Producing Aromatic Compound | TYR, XDH, CYP1A1 | SNCA 218/4885CTSV 3625/4885CTSL 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.