Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704047 | 0.86 | EGFR (0.44) | EGFRNSD2ESR2CA9MAPT | |
| SCHEMBL4624925 | 0.84 | KMT2A (0.60) | NSD2CA9MAPTTDP1MEN1 | |
| SCHEMBL767381 | 0.78 | NR1H4 (0.48) | ESR2CA9MAPTTDP1MEN1 | |
| SCHEMBL767153 | 0.77 | SENP1 (0.47) | ESR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL10908253 | 0.76 | KMT2A (0.56) | ESR2MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL767921 | 0.76 | MEN1 (0.50) | EGFRNSD2ESR2CA9MAPT | |
| SCHEMBL767669 | 0.76 | KMT2A (0.53) | ESR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL8756055 | 0.76 | KMT2A (0.49) | ESR2MAPTTDP1MEN1KMT2A | |
| SCHEMBL767601 | 0.75 | KMT2A (0.55) | MAPTMEN1KMT2A | |
| SCHEMBL12922697 | 0.73 | ALDH1A1 (0.46) | MAPTTDP1MEN1KMT2APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440632-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144393-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |