Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704046 | 0.86 | EGFR (0.47) | EGFRMAPTMEN1KMT2ATDP1 | |
| SCHEMBL4624925 | 0.84 | KMT2A (0.60) | MAPTMEN1KMT2ATDP1CA9 | |
| SCHEMBL767153 | 0.83 | SENP1 (0.47) | MAPTMEN1KMT2ATDP1NR1H4 | |
| SCHEMBL767381 | 0.81 | NR1H4 (0.48) | MAPTMEN1KMT2ATDP1NR1H4 | |
| SCHEMBL9335606 | 0.77 | KMT2A (0.58) | MAPTMEN1KMT2ATDP1CA9 | |
| SCHEMBL10908253 | 0.76 | KMT2A (0.56) | MAPTMEN1KMT2ANR1H4ESR2 | |
| SCHEMBL12922697 | 0.76 | ALDH1A1 (0.46) | MAPTMEN1KMT2ATDP1NR1H4 | |
| SCHEMBL767921 | 0.76 | MEN1 (0.50) | EGFRMAPTMEN1KMT2ATDP1 | |
| SCHEMBL7789344 | 0.74 | ESR2 (0.64) | MEN1KMT2APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL767669 | 0.73 | KMT2A (0.53) | MAPTMEN1KMT2ATDP1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440632-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144393-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |