Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843149 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ELMNAKCNMA1 | |
| SCHEMBL16261149 | 0.83 | LMNA (0.72) | ALDH1A1MAPTKDM4ELMNAKCNMA1 | |
| SCHEMBL16146937 | 0.83 | IRAK4 (0.60) | ALDH1A1MAPTKDM4EP2RX3HMOX1 | |
| SCHEMBL3045049 | 0.82 | KMT2A (0.52) | ALDH1A1MAPTLMNAKCNMA1HMOX1 | |
| Hydrochloric Acid SCHEMBL726186 | 0.81 | LMNA (0.70) | ALDH1A1MAPTKDM4ELMNAKCNMA1 | |
| SCHEMBL3412460 | 0.81 | ABL1 (0.53) | ALDH1A1MAPTLMNAKCNMA1HMOX1 | |
| SCHEMBL17040592 | 0.81 | TSHR (0.53) | ALDH1A1KDM4EGAASLC9A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3045694 | 0.81 | CSNK2A1 (0.47) | ALDH1A1LMNAHMOX1KMT2ASLC9A1 | |
| SCHEMBL17040662 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ELMNAKCNMA1 | |
| SCHEMBL3049895 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHMOX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |