Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385153 | 0.85 | TSHR (0.50) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11627993 | 0.84 | MEN1 (0.53) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL16261149 | 0.84 | LMNA (0.72) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL11314652 | 0.83 | TSHR (0.51) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL17040919 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL726186 | 0.83 | LMNA (0.70) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL17171668 | 0.83 | KDM4E (0.54) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL7244617 | 0.83 | HTR2A (0.52) | LMNAMAPTKDM4EGAATSHR | |
| SCHEMBL945720 | 0.82 | TSHR (0.65) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL18045688 | 0.81 | TSHR (0.58) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |