Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649137 | 0.80 | MTNR1A (0.42) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL3180689 | 0.79 | L3MBTL1 (0.61) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL732456 | 0.77 | NAMPT (0.57) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL12685839 | 0.76 | L3MBTL1 (0.56) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL23386279 | 0.76 | CA12 (0.46) | HDAC1NAMPTGAACA1HDAC6 | |
| SCHEMBL25738303 | 0.76 | CA12 (0.56) | GAACA1CA2BRD4TDP1 | |
| SCHEMBL13055397 | 0.76 | KDM4A (0.51) | L3MBTL1HDAC1NAMPTGAAKDM4A | |
| SCHEMBL5749285 | 0.76 | ERCC1 (0.56) | L3MBTL1HDAC1NAMPTGAACA1 | |
| SCHEMBL31709823 | 0.75 | BRD4 (0.54) | L3MBTL1HDAC1NAMPTKDM4AGLS | |
| SCHEMBL731764 | 0.75 | BRD4 (0.54) | L3MBTL1HDAC1NAMPTKDM4AGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239878-A1 | Novel Compounds for Imaging Tau Proteins That Accumulate In Brain | MAPT, FABP7, HTT | L3MBTL1 2624/4885HDAC1 1398/4885NAMPT 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.