SCHEMBL17041663

SCHEMBL17041663

COC1O[C@@H](COC(=O)c2ccc(-c3ccccc3)cc2)[C@H](OC(=O)c2ccc(-c3ccccc3)cc2)[C@@H]1OC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.56
PTPN2 P17706 1/20 0.47
PTPN11 Q06124 1/20 0.47
USP2 O75604 2/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
F11 P03951 2/20 0.46
TMPRSS2 O15393 1/20 0.46
PDE5A O76074 1/20 0.46
HMGCR P04035 1/20 0.46
CYP1A2 P05177 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
HSPD1 P10809 1/20 0.46
CYP2C9 P11712 1/20 0.46
CA6 P23280 1/20 0.46
TBXAS1 P24557 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18279612 1.00 PTPN1 (0.56) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL17041776 1.00 PTPN1 (0.56) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL8975481 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL15481989 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL12352428 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL8587293 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL11232105 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL22983992 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL22984008 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1
SCHEMBL10700635 0.93 PTPN1 (0.57) PTPN1PTPN2PTPN11USP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9884882-B2 Method for producing thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate FUJIFILM CORPORATION (JP) 2018-02-06 US disclosed
US-9884882-B2 Method for producing thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate FUJIFILM CORPORATION (JP) 2018-02-06 US disclosed
US-9884882-B2 Method for producing thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate FUJIFILM CORPORATION (JP) 2018-02-06 US disclosed
EP-3109245-B1 METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORP (JP) 2018-01-03 EP disclosed
EP-3109245-A1 METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM Corporation (JP) 2016-12-28 EP disclosed
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORPORATION (JP) 2016-12-08 US disclosed
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORPORATION (JP) 2016-12-08 US disclosed
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE FUJIFILM CORPORATION (JP) 2016-12-08 US disclosed
WO-2015125781-A1 METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE 富士フイルム株式会社 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160355536-A1 METHOD FOR PRODUCING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE ST6GAL1, FUT6, FUT5 PTPN1 2033/4885PTPN2 1966/4885PTPN11 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.