Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4836148 | 0.98 | S100B (0.61) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL11867613 | 0.86 | S100B (0.49) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL4817926 | 0.84 | S100B (0.58) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL11431090 | 0.81 | S100B (0.70) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL24426114 | 0.81 | S1PR1 (0.58) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL9763236 | 0.80 | CYP3A4 (0.45) | S100BALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL9192726 | 0.78 | S100B (0.44) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL11149905 | 0.78 | S100B (0.66) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL29350181 | 0.78 | S100B (1.00) | S100BALDH1A1CYP3A4L3MBTL1TDP1 | |
| SCHEMBL34104 | 0.78 | S100B (1.00) | S100BALDH1A1CYP3A4L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611797-B1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI SCIENCE CO LTD (KR) | 2016-12-28 | — | — | EP | disclosed |
| US-9068093-B2 | Surface modification of carbon black | EASTMAN KODAK COMPANY (US) | 2015-06-30 | — | — | US | disclosed |
| US-9068093-B2 | Surface modification of carbon black | EASTMAN KODAK COMPANY (US) | 2015-06-30 | — | — | US | disclosed |
| US-8835458-B2 | Quinoline or quinazoline derivatives with apoptosis inducing activity on cells | HANMI SCIENCE CO., LTD (KR) | 2014-09-16 | — | — | US | disclosed |
| EP-2611797-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | Hanmi Science Co., Ltd. (KR) | 2013-07-10 | — | — | EP | disclosed |
| US-20130165386-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI SCIENCE CO., LTD (KR) | 2013-06-27 | — | — | US | disclosed |
| WO-2012030160-A2 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | HANMI HOLDINGS CO., LTD. (KR) | 2012-03-08 | — | — | WO | disclosed |
| US-RE37693-E1 | NONLIGHT-SENSITIVE LAYER ON THE UPPERMOST SIDE OF AN EMULSION LAYER CONTAINS A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE-TYPE COMPOUND WHICH IS LIQUID AT ROOM TEMPERATURE; PREVENTS DETERIORATION OF SURFACE GLOSS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| US-5532138-A | Method and kits for determining peroxidatively active catalysts | BEHRINGWERKE AG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0177884-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1992-08-26 | — | — | EP | disclosed |
| EP-0095920-A2 | A color photographic light-sensitive material | KONICA CORPORATION (JP) | 1983-12-07 | — | — | EP | disclosed |
| EP-0095722-A2 | Color photographic materials | KONICA CORPORATION (JP) | 1983-12-07 | — | — | EP | disclosed |
| US-4409321-A | COLOR PHOTOGRAPHY | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4335197-A | SILVER HALIDE DISPERSION IN FILM-FORMING POLYMERIC COUPLER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0052942-A1 | Photoimaging process | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-06-02 | — | — | EP | disclosed |
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4233399-A | Photographic elements containing amino-substituted hydroxy-pyridones | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-11-11 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4182886-A | OPTICAL FILTERS IN COLOR PHOTOGRAPHY | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165386-A1 | QUINOLINE OR QUINAZOLINE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY ON CELLS | CASP7, API5, BAX | S100B 515/4885ALDH1A1 4307/4885CYP3A4 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.