Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17043096 | 1.00 | P2RX3 (0.48) | P2RX3ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL3847824 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHTTHPGD | |
| SCHEMBL3847829 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHTTHPGD | |
| SCHEMBL1306630 | 0.88 | P2RX3 (0.49) | P2RX3ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL1306633 | 0.88 | P2RX3 (0.49) | P2RX3ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL1307169 | 0.87 | P2RX3 (0.55) | P2RX3ALDH1A1KDM4EHTTHPGD | |
| SCHEMBL1307168 | 0.87 | P2RX3 (0.55) | P2RX3ALDH1A1KDM4EHTTHPGD | |
| SCHEMBL1306690 | 0.86 | P2RX3 (0.47) | P2RX3ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL3833477 | 0.86 | P2RX3 (0.47) | P2RX3ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL1306688 | 0.86 | P2RX3 (0.47) | P2RX3ALDH1A1KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913322-A2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | Korea Research Institute Of Chemical Technology (KR) | 2015-09-02 | — | — | EP | disclosed |