Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901724 | 0.90 | KARS1 (0.57) | KARS1SYK | |
| SCHEMBL901307 | 0.88 | KARS1 (0.77) | KARS1SYK | |
| SCHEMBL1704727 | 0.86 | KARS1 (0.54) | KARS1SYK | |
| SCHEMBL902605 | 0.85 | KARS1 (0.56) | KARS1SYK | |
| SCHEMBL1755661 | 0.85 | KARS1 (0.74) | KARS1SYK | |
| SCHEMBL901754 | 0.83 | KARS1 (0.58) | KARS1 | |
| SCHEMBL12469502 | 0.82 | KARS1 (0.74) | KARS1SYK | |
| SCHEMBL1704255 | 0.79 | KARS1 (0.52) | KARS1SYK | |
| SCHEMBL901741 | 0.78 | KARS1 (0.74) | KARS1SYK | |
| SCHEMBL901406 | 0.78 | KARS1 (0.50) | KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441755-A1 | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors | Almirall, S.A. (ES) | 2012-04-18 | — | — | EP | disclosed |