SCHEMBL170449

SCHEMBL170449

Cc1cc(-c2c(Cl)ccc3[nH]nnc23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 1/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
HSPA5 P11021 1/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
HIF1A Q16665 3/20 0.35
TP53 P04637 1/20 0.33
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PLG P00747 1/20 0.32
PLAU P00749 1/20 0.32
PRSS1 P07477 1/20 0.32
CYP2D6 P10635 1/20 0.32
HSD17B10 Q99714 1/20 0.32
AMY1A P0DUB6 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757181 1.00 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL29429258 1.00 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL29470088 0.88 HSP90AA1 (0.41) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL2356488 0.88 HSP90AA1 (0.41) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL29733675 0.88 HSP90AA1 (0.41) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL28203169 0.85 TP53 (0.31) SMN1; SMN2CYP2C9CYP2C19HIF1ATP53
SCHEMBL30162803 0.84 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL1925757 0.84 GABBR2 (0.32) PTGS1PTGS2
SCHEMBL27880219 0.84 TP53 (0.33) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL31621073 0.84 TRPA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307920-A Antibacterial material for new energy automobile interior trim and preparation method thereof 慈溪市山今高分子塑料有限公司 2024-07-09 CN claimed
CN-118271310-A Anodic electrochromic material, electrochromic composition and electrochromic device 比亚迪股份有限公司 2024-07-02 CN claimed
CN-118271302-A Carbazole compound and composition, preparation method and application thereof, and electrochromic device 比亚迪股份有限公司 2024-07-02 CN claimed
CN-118271311-A Anodic electrochromic material, electrochromic composition and electrochromic device 比亚迪股份有限公司 2024-07-02 CN claimed
CN-117866544-A PID-resistant EVA packaging adhesive film and preparation method and application thereof 中国石油化工股份有限公司 2024-04-12 CN claimed
CN-114773798-B High-impact long-acting yellowing-resistant PBT reinforced flame-retardant composite material and preparation method and application thereof 上海金发科技发展有限公司 2024-03-15 CN claimed
CN-117467398-A Printable OCA optical cement and preparation method thereof 广东鼎立森新材料有限公司 2024-01-30 CN claimed
CN-117467268-A Helmet buffer layer made of polyurethane powder material and manufacturing process thereof 新疆大学 2024-01-30 CN claimed
CN-117025052-A Water-based superhydrophobic consolidation material for TIT (tungsten inert gas) embedding seal layer 北京中科安途交通科技有限公司 2023-11-10 CN claimed
CN-116694284-A Rail transit forge welding sealant and preparation method thereof 杭州之江有机硅化工有限公司 2023-09-05 CN claimed
CN-111162170-A Perovskite thin film doped with ultraviolet absorber, preparation method and solar cell 杭州纤纳光电科技有限公司 2020-05-15 CN claimed
CN-107759983-B Patterned transparent back plate material 杭州福斯特应用材料股份有限公司 2020-03-24 CN claimed
CN-110862759-A Foamless fast deep-cured single-component modified PU court material and preparation method thereof 广东盛天体育股份有限公司 2020-03-06 CN claimed
CN-110804399-A Polyurethane structure adhesive film for soft connection of edges of cabin solidified at room temperature and preparation method thereof 黑龙江省科学院石油化学研究院 2020-02-18 CN claimed
CN-110739404-A Quantum dot light-emitting diode and preparation method thereof TCL集团股份有限公司 2020-01-31 CN claimed
CN-108207443-B PE mulching film 东莞市正新包装制品有限公司 2020-01-24 CN claimed
CN-1990601-B Composition, composition manufacturing method, thermosensitive adhesive material, and information recording material RICOH CO LTD 2010-12-15 CN claimed
EP-1879950-A2 POLY(ARYLENE ETHER) COMPOSITIONS WITH IMPROVED ULTRAVIOLET LIGHT STABILITY, AND RELATED ARTICLES General Electric Company (US) 2008-01-23 EP claimed
WO-2006118832-A2 POLY(ARYLENE ETHER) COMPOSITIONS WITH IMPROVED ULTRAVIOLET LIGHT STABILITY, AND RELATED ARTICLES GENERAL ELECTRIC COMPANY (US) 2006-11-09 WO claimed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US claimed