Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356488 | 0.84 | HSP90AA1 (0.41) | PTGS2ALOX5 | |
| SCHEMBL29733675 | 0.84 | HSP90AA1 (0.41) | PTGS2ALOX5 | |
| SCHEMBL170449 | 0.84 | SMN1; SMN2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL29470088 | 0.84 | HSP90AA1 (0.41) | PTGS2ALOX5 | |
| SCHEMBL29757181 | 0.84 | SMN1; SMN2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL29429258 | 0.84 | SMN1; SMN2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL28203169 | 0.81 | TP53 (0.31) | — | |
| SCHEMBL27880219 | 0.80 | TP53 (0.33) | — | |
| SCHEMBL6551244 | 0.79 | CA2 (0.40) | — | |
| SCHEMBL28480882 | 0.76 | AMY1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328953-A1 | SILICON CONTAINING POLYMERIC MATERIALS | Advanced Medical Optics, Inc. (US) | 2011-06-08 | — | — | EP | disclosed |