Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070790 | 0.87 | POLB (0.48) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL738179 | 0.81 | MEN1 (0.50) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL4419395 | 0.78 | MEN1 (0.63) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL7275635 | 0.77 | RAB9A (0.55) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL17044822 | 0.77 | LMNA (0.49) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL7258664 | 0.77 | RAB9A (0.58) | RAB9AMEN1CYP1A2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL9725349 | 0.76 | RAB9A (0.64) | RAB9AMEN1CYP1A2KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7265768 | 0.76 | RAB9A (0.57) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL7272271 | 0.76 | RAB9A (0.57) | RAB9AMEN1CYP1A2KMT2APOLB | |
| SCHEMBL15255347 | 0.76 | RAB9A (0.67) | RAB9AMEN1CYP1A2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082819-B1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2020-06-17 | — | — | EP | disclosed |
| US-20150246890-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS LLC | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246890-A1 | SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | PRKCQ, PRKCH, PRKCE | RAB9A 2324/4885MEN1 3777/4885CYP1A2 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.