Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7265768 | 0.99 | RAB9A (0.57) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL15255347 | 0.84 | RAB9A (0.67) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL4419395 | 0.84 | MEN1 (0.63) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9725349 | 0.82 | RAB9A (0.64) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL8248960 | 0.79 | LMNA (0.64) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL7092639 | 0.78 | RAB9A (0.67) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL9725381 | 0.78 | RAB9A (0.71) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL3639398 | 0.78 | OPRM1 (0.67) | ALDH1A1 | |
| SCHEMBL7258664 | 0.77 | RAB9A (0.58) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL17044905 | 0.77 | RAB9A (0.52) | RAB9AMEN1CYP1A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268148-B1 | TETRAHYDRONAPHTHALENE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| US-4808605-A | Tetrahydronaphthalene derivatives as calcium antagonists | HOFFMANN-LA ROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |