SCHEMBL17045258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21243716	0.86	EPHX1 (0.52)	ANPEP
	SCHEMBL21243718	0.86	EPHX1 (0.52)	ANPEP
	SCHEMBL21314284	0.84	PNMT (0.46)	SLC6A4SLC6A2SLC6A3DPP4DPP7
	SCHEMBL21314262	0.84	PNMT (0.46)	SLC6A4SLC6A2SLC6A3DPP4DPP7
	SCHEMBL21314254	0.83	PNMT (0.49)	DPP4DPP7ANPEPENPEPDPP8
	SCHEMBL17045246	0.81	EPHX1 (0.41)	DPP4DPP7ANPEPFAPDPP8
	SCHEMBL17045266	0.80	DPP4 (0.46)	DPP4DPP7ANPEPCYP2C19DPP8
	SCHEMBL21314259	0.80	HDAC8 (0.44)	DPP4DPP7FAPDPP8DPP9
	SCHEMBL21314258	0.80	HDAC8 (0.44)	DPP4DPP7FAPDPP8DPP9
	SCHEMBL21314265	0.79	SLC6A4 (0.50)	SLC6A4SLC6A2SLC6A3DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.