SCHEMBL17045280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24017152	0.83	PNMT (0.74)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL24017049	0.83	PNMT (0.74)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL1570139	0.82	PNMT (0.71)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL266685	0.82	PNMT (1.00)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL14478283	0.82	PNMT (1.00)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL3335737	0.82	PNMT (0.60)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL30363681	0.82	PNMT (1.00)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL8153800	0.80	PNMT (0.69)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL7489958	0.80	PNMT (0.69)	PNMTTAAR1IDO1CYP3A4AGXT
	SCHEMBL1570196	0.80	PNMT (0.69)	PNMTTAAR1IDO1CYP3A4AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.