SCHEMBL24017152

SCHEMBL24017152

NC(Cc1cccc(Cl)c1)C(N)Cc1cccc(Cl)c1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.74
TAAR1 Q96RJ0 4/20 0.55
IDO1 P14902 4/20 0.53
CYP3A4 P08684 2/20 0.53
AGXT P21549 2/20 0.53
HTR3E A5X5Y0 3/20 0.50
HTR3B O95264 3/20 0.50
HTR3A P46098 3/20 0.50
HTR3D Q70Z44 3/20 0.50
HTR3C Q8WXA8 3/20 0.50
TACR1 P25103 2/20 0.49
CHRM2 P08172 1/20 0.48
AOC3 Q16853 1/20 0.47
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017049 1.00 PNMT (0.74) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL4694047 0.88 PNMT (0.76) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL30363681 0.85 PNMT (1.00) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL1570139 0.85 PNMT (0.71) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL14478283 0.85 PNMT (1.00) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL266685 0.85 PNMT (1.00) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL14018976 0.83 PNMT (0.69) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL17045280 0.83 PNMT (0.69) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL8153800 0.83 PNMT (0.69) PNMTTAAR1IDO1CYP3A4AGXT
SCHEMBL1570196 0.83 PNMT (0.69) PNMTTAAR1IDO1CYP3A4AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed