Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704085 | 0.81 | SYK (0.49) | SYK | |
| SCHEMBL902168 | 0.77 | SYK (0.49) | SYK | |
| SCHEMBL1704543 | 0.77 | SYK (0.49) | SYK | |
| SCHEMBL901783 | 0.77 | KARS1 (0.56) | SYK | |
| SCHEMBL901796 | 0.70 | KARS1 (0.45) | SYK | |
| SCHEMBL1704569 | 0.69 | SYK (0.46) | SYK | |
| SCHEMBL1704571 | 0.69 | SYK (0.46) | SYK | |
| SCHEMBL16875986 | 0.68 | SYK (0.59) | SYK | |
| SCHEMBL15990843 | 0.68 | SYK (0.76) | SYK | |
| SCHEMBL12469310 | 0.67 | KARS1 (0.56) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441755-A1 | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors | Almirall, S.A. (ES) | 2012-04-18 | — | — | EP | disclosed |