Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704409 | 0.87 | KARS1 (0.73) | KARS1SYK | |
| SCHEMBL902051 | 0.86 | KARS1 (0.55) | KARS1SYK | |
| SCHEMBL901900 | 0.86 | KARS1 (0.53) | KARS1SYK | |
| SCHEMBL901752 | 0.84 | KARS1 (0.73) | KARS1 | |
| SCHEMBL901758 | 0.82 | KARS1 (0.49) | KARS1SYK | |
| SCHEMBL901977 | 0.81 | KARS1 (0.65) | KARS1SYK | |
| SCHEMBL1704085 | 0.80 | SYK (0.49) | KARS1SYK | |
| SCHEMBL1704545 | 0.77 | SYK (0.48) | SYK | |
| SCHEMBL1704297 | 0.77 | SYK (0.53) | KARS1SYK | |
| SCHEMBL901891 | 0.76 | KARS1 (0.73) | KARS1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441755-A1 | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors | Almirall, S.A. (ES) | 2012-04-18 | — | — | EP | disclosed |
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |