SCHEMBL17046232

SCHEMBL17046232

CCC(C)N([SiH2]c1ccccc1)C1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.35
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
KDM4E B2RXH2 3/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 4/20 0.34
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NPC1 O15118 1/20 0.32
MITF O75030 1/20 0.32
RAB9A P51151 1/20 0.32
PAX8 Q06710 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17045941 0.98 L3MBTL1 (0.38) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17046114 0.83 KDM4E (0.41) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17046093 0.81 KDM4E (0.44) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17046202 0.77 SHBG (0.32)
SCHEMBL19149994 0.76 L3MBTL1 (0.35) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17046217 0.75 SHBG (0.35) KMT2AMEN1ALDH1A1
SCHEMBL19150106 0.75 L3MBTL1 (0.37) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17053491 0.75 SHBG (0.33)
SCHEMBL17046168 0.73 DRD3 (0.40) L3MBTL1KMT2AMEN1KDM4EUSP2
SCHEMBL17053490 0.73 SHBG (0.37) KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294250-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2019-05-21 US disclosed
EP-3395822-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME Versum Materials US, LLC (US) 2018-10-31 EP disclosed
US-9758534-B2 Organoaminosilanes and methods for making same VERSUM MATERIALS US, LLC (US) 2017-09-12 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20170204120-A1 Organoaminosilanes and Methods for Making Same VERSUM MATERIALS US, LLC (US) 2017-07-20 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-06-16 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-9233990-B2 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-12 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
EP-2913334-A1 Organoaminosilanes and methods for making same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150246937-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT L3MBTL1 471/4885KMT2A 170/4885MEN1 316/4885
US-20170204120-A1 Organoaminosilanes and Methods for Making Same DDAH1, IDUA, DDT L3MBTL1 471/4885KMT2A 170/4885MEN1 316/4885
US-10294250-B2 Organoaminosilanes and methods for making same DDAH1, IDUA, DDT L3MBTL1 471/4885KMT2A 170/4885MEN1 316/4885
US-20160168169-A1 ORGANOAMINOSILANES AND METHODS FOR MAKING SAME DDAH1, IDUA, DDT L3MBTL1 471/4885KMT2A 170/4885MEN1 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.