Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979162 | 0.83 | NPC1 (0.41) | ICAM1SELENPC1RAB9A | |
| SCHEMBL92906 | 0.81 | DRD4 (0.47) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL1704760 | 0.81 | L3MBTL1 (0.40) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL31073145 | 0.79 | ICAM1 (0.42) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL1704863 | 0.79 | L3MBTL1 (0.41) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL1705151 | 0.79 | L3MBTL1 (0.38) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL20985435 | 0.78 | ALDH1A1 (0.38) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL17857406 | 0.78 | KMT2A (0.36) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL8127296 | 0.77 | KDM4C (0.42) | ICAM1SELEL3MBTL1MEN1KMT2A | |
| SCHEMBL10214541 | 0.75 | L3MBTL1 (0.47) | L3MBTL1KDM4CTACR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357178-B1 | Process for the production of L-2-[18F]fluor-phenylalanine and 6-[18F]fluor-L-meta-tyrosine and their alpha-alkylated derivatives from a precursor. | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8273793-B2 | Method for producing precursors for L-2- [18F] fluorophenylalanine and 6- [18F] fluoro-L—meta-tyrosine and the α-methylated derivatives thereof, precursor, and method for producing L-2- [18F] fluorophenylalanine and 6- [18F] fluoro-L-meta-tyrosine and the α-methylated derivatives from the precursor | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273793-B2 | Method for producing precursors for L-2- [18F] fluorophenylalanine and 6- [18F] fluoro-L—meta-tyrosine and the α-methylated derivatives thereof, precursor, and method for producing L-2- [18F] fluorophenylalanine and 6- [18F] fluoro-L-meta-tyrosine and the α-methylated derivatives from the precursor | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2012-09-25 | — | — | US | disclosed |
| EP-2222644-B9 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE ALPHA -METHYLATED DERIVATIVES THEREOF AND THE PRECURSORS | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2222644-B9 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE ALPHA -METHYLATED DERIVATIVES THEREOF AND THE PRECURSORS | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| EP-2357178-A1 | Process for the production of L-2-[18F]fluor-phenylalanine and 6-[18F]fluor-L-meta-tyrosine and their alpha-alkylated derivatives from a precursor | Forschungszentrum Jülich GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| EP-2357178-A1 | Process for the production of L-2-[18F]fluor-phenylalanine and 6-[18F]fluor-L-meta-tyrosine and their alpha-alkylated derivatives from a precursor | Forschungszentrum Jülich GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| EP-2222644-B1 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE ALPHA -METHYLATED DERIVATIVES THEREOF AND THE PRECURSORS | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2011-08-03 | — | — | EP | disclosed |
| EP-2222644-B1 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE ALPHA -METHYLATED DERIVATIVES THEREOF AND THE PRECURSORS | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100256389-A1 | METHOD FOR PRODUCING PRECURSORS FOR L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L--META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L-META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES FROM THE PRECURSOR | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2010-10-07 | — | — | US | disclosed |
| US-20100256389-A1 | METHOD FOR PRODUCING PRECURSORS FOR L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L--META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L-META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES FROM THE PRECURSOR | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2010-10-07 | — | — | US | disclosed |
| EP-2222644-A2 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE ALPHA -METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L-META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES FROM THE PRECURSOR | Forschungszentrum Jülich GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009071050-A2 | METHOD FOR PRODUCING PRECURSORS FOR L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L--META-TYROSINE AND THE α-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2-[18F]FLUOROPHENYLALANINE AND 6-[18F]FLUORO-L-META-TYROSINE AND THE α-METHYLATED DERIVATIVES FROM THE PRECURSOR | Forschungszentrum Jülich GmbH (DE) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256389-A1 | METHOD FOR PRODUCING PRECURSORS FOR L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L--META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-2- [18F] FLUOROPHENYLALANINE AND 6- [18F] FLUORO-L-META-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES FROM THE PRECURSOR | TH, TYR, COMT | ICAM1 4479/4885SELE 4080/4885L3MBTL1 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.