Sugi Predict

Sugi Predict / Compounds / SCHEMBL10214541

SCHEMBL10214541

SCHEMBL10214541

Fc1cccc(COC2CCCCO2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ TACR1 P25103 1/20 0.46
▸ IDO1 P14902 2/20 0.45
▸ AGXT P21549 2/20 0.45
▸ CARM1 Q86X55 1/20 0.43
▸ PRMT6 Q96LA8 1/20 0.43
▸ PRMT8 Q9NR22 1/20 0.43
▸ KDM4C Q9H3R0 1/20 0.41
▸ SIGMAR1 Q99720 3/20 0.41
▸ GRM5 P41594 2/20 0.41
▸ TMEM97 Q5BJF2 1/20 0.40
▸ MAOB P27338 3/20 0.40
▸ LMNA P02545 1/20 0.40
▸ DRD4 P21917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10987183 0.85 L3MBTL1 (0.47) L3MBTL1ATMTACR1IDO1KDM4C
SCHEMBL29865973 0.83 CA2 (0.45) IDO1AGXTCARM1PRMT6KDM4C
SCHEMBL16318881 0.83 KDM4C (0.41) L3MBTL1TACR1KDM4CLMNA
SCHEMBL7852875 0.83 CA2 (0.45) IDO1AGXTCARM1PRMT6KDM4C
SCHEMBL1732627 0.83 KDM4C (0.41) L3MBTL1TACR1KDM4CLMNA
SCHEMBL23662562 0.83 DHFR (0.43) L3MBTL1TACR1AGXTKDM4CMAOB
SCHEMBL92943 0.83 KDM4C (0.41) L3MBTL1TACR1CARM1PRMT6KDM4C
SCHEMBL2767753 0.83 CYP4F2 (0.46) L3MBTL1TACR1IDO1KDM4CMAOB
SCHEMBL7338156 0.83 KDM4C (0.41) L3MBTL1TACR1KDM4CLMNA
SCHEMBL92954 0.82 NAAA (0.47) TACR1AGXTCARM1PRMT6PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2017-03-09 — — US disclosed
US-9572823-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-21 — — US disclosed
US-9566290-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9566290-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9566289-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9566289-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-02-14 — — US disclosed
US-9549938-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2017-01-24 — — US disclosed
US-20160228463-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-08-11 — — US disclosed
US-20160228463-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-08-11 — — US disclosed
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-07-21 — — US disclosed
US-20130064783-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-14 — — US disclosed
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-20120289686-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2012-11-15 — — US disclosed
US-8115026-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2012-02-14 — — US disclosed
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2010-10-21 — — US disclosed
US-7767657-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2010-08-03 — — US disclosed
US-20070155699-A1 Boron-containing small molecules ANACOR PHARMACEUTICALS (US) 2007-07-05 — — US disclosed
US-20070155699-A1 Boron-containing small molecules ANACOR PHARMACEUTICALS (US) 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160206638-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20130059802-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20170066787-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20160228463-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20120289686-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20130059803-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20070155699-A1 Boron-containing small molecules ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20100267981-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885
US-20130064783-A1 BORON-CONTAINING SMALL MOLECULES ETF1, POLR1C, DPM1 L3MBTL1 1024/4885ATM 4841/4885TACR1 1867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.