Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.34 |
| ▸ | KDR | P35968 | 6/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MST1R | Q04912 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048785 | 0.82 | CNR1 (0.32) | — | |
| SCHEMBL17048866 | 0.77 | MET (0.34) | METKDRFGFR2AXLFLT3 | |
| SCHEMBL17048975 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL17048815 | 0.76 | TDP1 (0.33) | METKDRFGFR2AXLFLT3 | |
| SCHEMBL17048776 | 0.76 | MAPT (0.37) | — | |
| SCHEMBL5078043 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL17048914 | 0.69 | MET (0.40) | METKDRFGFR2AXLFLT3 | |
| Hydrochloric Acid SCHEMBL17048923 | 0.68 | MET (0.40) | METKDRFGFR2AXLFLT3 | |
| SCHEMBL17048880 | 0.67 | — | — | |
| SCHEMBL17048813 | 0.65 | ALDH1A1 (0.45) | METKDRFGFR2AXLFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-A1 | PYRAZOLE AMIDE DERIVATIVE | Teijin Pharma Limited (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015129926-A1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2015-09-03 | — | — | WO | disclosed |