SCHEMBL17048975 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.31

▸	CYP1A2	P05177	1/20	0.31

▸	CYP3A4	P08684	1/20	0.31

▸	CYP2C9	P11712	1/20	0.31

▸	CYP2C19	P33261	1/20	0.31

▸	L3MBTL1	Q9Y468	1/20	0.31

▸	TSHR	P16473	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17048868	0.77	MET (0.34)	—
SCHEMBL17048776	0.76	MAPT (0.37)	ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5078043	0.75	ALDH1A1 (0.36)	ALDH1A1TSHR
SCHEMBL17048875	0.74	GPR35 (0.36)	ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL17048974	0.73	ALDH1A1 (0.33)	ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL17048986	0.63	TSHR (0.31)	TSHR
SCHEMBL17048874	0.62	ALDH1A1 (0.42)	ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL17057122	0.61	ALDH1A1 (0.30)	ALDH1A1
SCHEMBL9495799	0.60	TSHR (0.67)	ALDH1A1CYP3A4TSHR
SCHEMBL17048740	0.59	USP7 (0.30)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3110810-A1	PYRAZOLE AMIDE DERIVATIVE	Teijin Pharma Limited (JP)	2017-01-04	—	—	EP	disclosed
WO-2015129926-A1	PYRAZOLE AMIDE DERIVATIVE	TEIJIN PHARMA LIMITED (JP)	2015-09-03	—	—	WO	disclosed