SCHEMBL17049068

SCHEMBL17049068

Cc1ccc(C=O)nc1Br

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.46
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.35
RRM2 P31350 1/20 0.34
TERT O14746 2/20 0.33
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
CYP2A6 P11509 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6629423 0.77 CCR1 (0.50) CCR1ALDH1A1RRM2TERTTSHR
SCHEMBL12715713 0.76 CCR1 (0.61) CCR1ALDH1A1MAPT
SCHEMBL20057394 0.75 TDP1 (0.33) TDP1
SCHEMBL1574734 0.74 CCR1 (0.46) CCR1ALDH1A1RRM2TERTTRIM24
SCHEMBL3046961 0.74 CCR1 (0.46) CCR1ALDH1A1RRM2TERTMAPT
SCHEMBL25207516 0.74 CCR1 (0.46) CCR1ALDH1A1TDP1RRM2TERT
SCHEMBL1979692 0.74 CCR1 (0.46) CCR1ALDH1A1RRM2TERTTRIM24
SCHEMBL15104564 0.74 CCR1 (0.46) CCR1ALDH1A1RRM2TERTTRIM24
SCHEMBL29953577 0.74 CCR1 (0.46) CCR1ALDH1A1RRM2TERTTSHR
SCHEMBL20110641 0.74 CCR1 (0.46) CCR1ALDH1A1TERTTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183230-A1 COMPOUNDS CONTAINING BENZOSULTAM SUZHOU GENHOUSE BIO CO., LTD. (CN) 2023-06-15 US disclosed
US-10005741-B2 Therapeutic compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-06-26 US disclosed
US-10005741-B2 Therapeutic compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-06-26 US disclosed
US-20180141921-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-05-24 US disclosed
US-20180141921-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-05-24 US disclosed
US-9908856-B2 Therapeutic compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-03-06 US disclosed
US-9908856-B2 Therapeutic compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-03-06 US disclosed
US-20170008859-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-01-12 US disclosed
US-20170008859-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-01-12 US disclosed
US-20170008859-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2017-01-12 US disclosed
WO-2015130973-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2015-09-03 WO disclosed
WO-2015130973-A1 THERAPEUTIC COMPOUNDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008859-A1 THERAPEUTIC COMPOUNDS IAPP, PARK7, NLN CCR1 3841/4885ALDH1A1 854/4885TDP1 2381/4885
US-20180141921-A1 THERAPEUTIC COMPOUNDS IAPP, PARK7, NLN CCR1 3841/4885ALDH1A1 854/4885TDP1 2381/4885
US-10005741-B2 Therapeutic compounds IAPP, PARK7, NLN CCR1 3841/4885ALDH1A1 854/4885TDP1 2381/4885
US-20230183230-A1 COMPOUNDS CONTAINING BENZOSULTAM TBXA2R, TBXAS1, SULT2A1 CCR1 4211/4885ALDH1A1 299/4885TDP1 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.